Protein Is Cash 2010

June, 2010



2010 LAB MANUAL (Click to Download)


March 6, 13, 20, 27, April 10th University of Rhode Island, at Providence, RI
March 22-25th Hudson Valley CC at Troy, NY
April 20-23rd Minuteman Technical HS, Lexington, MA
June 14-18th Hillsborough CC at Brandon, FL
June 22-26th Mesa CC at Mesa, AZ
Day One ~ Facilities and Metrology
Power Point Overview:     So, What Is Biomanufacturing?
Power Point Laboratory:     Metrology Instrumentation and Its Limits
Power Point Laboratory:     Pipette Calibration
Video:     Mike Cicio, Bench Top to Bottle
Article 1:     Biotech Set To Dominate Drug Industry Growth, Evaluate Pharma, June 17, 2009 
Article 2:     Biotech, The Community Way, Nature, Volume 458, March 2009

Day Two ~ Transformation and Upstream Processing
Power Point Overview:     Discovery Research and Cell Culture
Power Point Laboratory:     Transformation and Production
Video:     Tim Charlebois, Technology and Opportunities in Mammalian Cell Culture
Article 1:     Arnold Demain, Microbial Biotechnology
Article 2:     Arnold Demain, Small Bugs Big Business: The Economic Power of the Microbe
Article 3:     Tilman Gerngross, Therapeutics in Yeast
Article 4:     GlycoFi, Scientists Report Full Humanization of Yeast Glycosylation Pathway
Article 5:     Florian M Wurm, Therapeutics in Animal Cells
Article 6:     Ian Freshney, Culture of Animal Cells - Scale Up
Article 7:     Kristof De Schutter et al, Genome sequence of the recombinant protein production host Pichia pastoris
Article 8:     A. Varki et al, Essentials of glycobiology
Image 1:     Pichia pastoris
Image 2:     Escherichia coli
Image 3:     CHO Cells
Animation:     Inner Life of the Cell

Day Three ~ Downstream Processing
Power Point Overview:     Downstream Processing in Biopharmaceutical Manufacturing
Power Point Laboratory:     Introduction to GFP Chromatography
Virtual Laboratory:     Virtual Chromatography Laboratory (to login enter your email address and the password: teachbio)
Article 1:     GFP The green fluorescent protein: discovery, expression and development (Nobel Address 2008)
Article 2:     Purification by Liquid Chromatography
Animation:     Column Chromatography
Order Free Poster:     Fluorescent Proteins Illuminate Cell Biology
or View and Print Poster
and View and Print Supplementary Information

Day Four ~ Quality Control Biochemistry
Power Point Overview:     Quality Control Biochemistry
Power Point Laboratory:     SDS-PAGE

Day Five ~ Pre-Clinical Animal and Human Clinical Trials
Power Point Overview:     Clinical Trials
Power Point Laboratory:     FDA API Inspections
Video:     Barbara Immel, cGMPs in Biopharmaceutical Manufacturing
Article 1:     Barbara Immel, A Brief History of the GMPs
Article 2:     Biomanufacturing Acronyms
Article 3:     Gary Walsh, Biopharmaceutical Benchmarks, Table of Biopharmaceuticals
Article 4:     Thomson Reuters, This Years New Drugs and Biologics -2009
Article 5:     Fresh from the Biologic Pipeline - 2009: Human antibodies take center stage, as they pile up in the list of approved biologics in 2009.

Appendix: Biotechnology/Biomanufacturing Careers
ATV TV Video 1:     What Is Biomanufacturing?
ATV TV Video 2:     Student Profiles
ATV TV Video 3:     Products From Living Cells
ATV TV Video 4:     What Is An SOP?
ATV TV Video 5:     Community College Programs
ATV TV Video 6:     Influencing Quality of Life

Rhode Island Protein Is Cash Workshop Attendees and Instructors
Rhode Island
Consortium, Providence, RI

March 6, 13, 20, 27, April 10, 2010
    View Workshop Agenda
View RI HS Preparation in Bioscience & Math

Albany Area
Consortium, Troy, NY

March 22-25, 2010
    View Workshop Agenda
Video from Community Television
( from Albany/Schenectady/Troy)

Photo Slideshow (Greg Panzanaro)
View NY HS Preparation in Bioscience & Math
Marine Biotechnology in Berlin, NY

Minuteman Reg. HS
Lexington, MA

April 20-23, 2010
    View Workshop Agenda
Photo Slideshow
Massachusetts Genetown Map
View MA HS Preparation in Bioscience & Math

Hillsborough CC
Tampa, FL

June 14-18, 2010

Mesa CC
Mesa, AZ

June 22-26, 2010
    View Workshop Agenda
Arizona City OKs $200K for Life Sciences

View AZ HS Preparation in Bioscience & Math